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个人简介

已在Chem. Commun.,Org. Lett.J. Org. Chem.Chemistry A European   Journary等顶级期刊上发表近20篇高水平的学术论文。2014年6月回国以来,独立开展了羧酸作为合成子构筑碳氮键的主要工作(Org. Lett.,   2016,   18, 55605563Org. Biomol. Chem., 2018,   16, 2421–2426J. Org. Chem., 2018, 83, 82338240Adv. Syn. Catal.,   2019, 361, 192 –200)

1、发现分子内脱羧胺化IDA 反应

2、多金属氧簇催化的脱羧C-N偶联

研究领域和方向

1. 脱羧偶联构筑C-N、C-C键(IDA 反应)
2. 多酸、有机金属和有机小分子的合成与催化方法学
3. 天然产物全合成

教育背景

2006.09-2011.07 兰州大学,化学专业,理学博士
2000.9-2004.7 兰州大学,化学专业,理学学士

工作履历

2014.09-至今 IM体育官方网站,副研究员
2011.07-2014.06 美国Colorado State University、University of Alabama at Birmingham、 University of Texas at San Antonio,博士后
2004.07-2006.08 上海药明康德新药开发有限公司,高级技术员

研究成果

已在Chem. Commun.,Org. Lett.;J. Org. Chem.;Chemistry A European Journary等顶级期刊上发表近20篇高水平的学术论文。2014年6月回国以来,独立开展了羧酸作为合成子构筑碳氮键的主要工作(Org. Lett., 2016, 18, 5560−5563;Org. Biomol. Chem., 2018, 16, 2421–2426;J. Org. Chem., 2018, 83, 8233−8240;Adv. Syn. Catal., 2019, 361, 192 –200)。
代表性论文
1. Hui Fu, Peihe Li, Zheng Wang, Xiaoying Li, Qipu Dai*, and Changwen Hu. Synthesis of the protected α- amino acid via decarboxylation amination from malonate derivatives. Org. Biomol. Chem., 2020,18, 4439-4446.
2. Qipu Dai, Baoguo Zhao, Yihui Yang, and Yian Shi*. Pd-Catalyzed Oxidative Heck Reaction of Grignard Reagents with Diaziridinone as Oxidant. Org. Lett., 2019, 21, 5157−5161.
3. Zheng Wang, Peihe Li, Hui Fu, Qipu Dai*, and Changwen Hu*. Pd-Catalyzed Synthesis of Indolines through Decarboxylative Amination/Annulation Pathways from Aroyloxycarbamates. Adv. Syn. Catal., 2019, 361, 192 –200.
4. Peihe Li, Zheng Wang, Hui Fu, Qipu Dai*, and Changwen Hu*. Cu(I)/{Nb6O19} Catalyzed N-Acylation of Arylacetic Acids with Amines under Aerobic Conditions. Chem. Commun., 2018, 54, 12471—12474.
5. Peihe Li, Nuannuan Ma, Zheng Wang, Qipu Dai*, and Changwen Hu*. Base-Mediated Intramolecular Decarboxylative Synthesis of Alkylamines from Alkanoyloxycarbamates. J. Org. Chem., 2018, 83, 8233−8240.
6. Nuannuan Ma, Peihe Li, Zheng Wang, Qipu Dai*, and Changwen Hu*. Synthesis of Indoles from Aroyloxycarbamates with Alkynes via Decarboxylation/Cyclization. Org. Biomol. Chem., 2018, 16, 2421–2426.
7. Peihe Li, Nuannuan Ma, Jikun Li, Zheng Wang, Qipu Dai*, and Changwen Hu*. Regioselective Synthesis of 2‑Vinylanilines Using O‑aroyloxycarbamates by Sequential Decarboxylation/Amination/Heck Reaction. J. Org. Chem., 2017, 82, 8251−8257.
8. Qipu Dai#*, Peihe Li#, Nuannuan Ma, and Changwen Hu*. Palladium-Catalyzed Decarboxylative Synthesis of Arylamines. Org. Lett., 2016, 18, 5560−5563.
9. Pengfei Wang*, Dattatray A. Devalankar, Qipu Dai, Ping Zhang*, and Suzanne M. Michalek*. Synthesis and Evaluation of QS-21-Based Immunoadjuvants with a Terminal-Functionalized Side Chain Incorporated in the West Wing Trisaccharide. J. Org. Chem., 2016, 81, 9560−9566.
10. Pengfei Wang*, Qipu Dai, Punith Thogaripally, Ping Zhang, and Suzanne M. Michalek . Expeditious Synthesis of QS‐21‐Based Immunoadjuvants. J. Org. Chem., 2013, 78, 11525–11534.
11. Qipu Dai, Nirmal K. Rana, and John Cong-Gui Zhao*. Highly Stereoselective Synthesis of 2,6-cis-Substituted Tetrahydropyrans Using a One-Pot Sequential Catalysis. Org. Lett., 2013, 15, 2922-2925.
12. Qipu Dai, Huicai Huang, and John Cong-Gui Zhao*. Highly Stereoselective Synthesis of Trisubstituted Cyclohexanols Using a Guanidine-Catalyzed Tandem Henry-Michael Reaction. J. Org. Chem., 2013, 78, 4153-4157. Highlighted by Organic-Chemistry.org
13. Qipu Dai, Hadi Arman, and John Cong-Gui Zhao*. One-Pot Sequential Organocatalysis: Highly Stereoselective Synthesis of Trisubstituted Cyclohexanols. Chemistry A European Journal 2013, 19, 1666 – 1671. Highlighted by Organic-Chemistry.org
14. Qipu Dai, Xingang Xie, Shiyan Xu, Donghui Ma, Shibing Tang, and Xuegong She*. Total Syntheses of Tardioxopiperazine A, Isoechinulin A and Variecolorin C. Org. Lett., 2011, 13, 2302-2305.